Apolipoprotein E, cognitive function, and cognitive decline among older Taiwanese adults

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Apolipoprotein E, B vitamins, and cognitive function in older adults.

Recognition of dated and contemporary famous faces, short-term memory, and visuospatial abilities were investigated in adults aged 75 years and older as a function of apolipoprotein E (APOE) genotype, epsilon4 or not epsilon4, and whether participants recorded normal or low levels of B vitamins. No associations between B vitamins and APOE were identified in respect to short-term memory or visuo...

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Apolipoprotein E, health, and mortality in Taiwanese older adults

Apolipoprotein E (ApoE), a commonly investigated genetic marker, has been linked to health outcomes and longevity. ApoE has three common alleles: E2, E3, and E4, with E3 being the most prevalent allele in most populations. The E4 allele is a common genetic risk factor for Alzheimer’s and cardiovascular disease (Corder et al., 1996; Eichner et al., 2002; Lahoz et al., 2001; Rosvall et al., 2009)...

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Neighborhood psychosocial environment, apolipoprotein E genotype, and cognitive function in older adults.

CONTEXT The social environment may influence cognitive function in aging. However, to our knowledge, no studies have investigated whether specific genes modify this association. OBJECTIVE To examine whether the apolipoprotein E (APOE) ε4 allele modifies the association of neighborhood psychosocial hazards and cognitive function. DESIGN A cross-sectional analysis. SETTING The Baltimore Mem...

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Predicting cognitive decline in healthy older adults.

OBJECTIVE Authors performed a neuropsychological determination of which individuals in a group of community-dwelling, healthy elderly volunteers would develop cognitive decline. METHODS A group of 155 volunteers reporting good memory and thinking participated in a prospective study over 4 years. Authors monitored cognitive functioning and incidence of Mild Cognitive Impairment (MCI)/Alzheimer...

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Cognitive function and oral health among community-dwelling older adults.

BACKGROUND Both oral health problems and cognitive impairment are relatively common among older adults. Poorer oral health appears to contribute to a decline in quality of life and to be related to various medical conditions. Little is known about the relationship of cognitive function to oral health among community-dwelling older adults. METHODS The sample included 1984 dentate community-dwe...

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ژورنال

عنوان ژورنال: PLOS ONE

سال: 2018

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0206118